$25 for $50 Worth of Customized T-shirts and Gifts from CafePress.
$15 for $50 Worth of Photo Books, Cards, and More from Mixbook.
The above are both Chicago deals (you do not have to live in Chicago to purchase them).
Go here for details.
$25 for $75 Worth of Wine from Wine Insiders' Online Store.
$25 for Five Baby Genius DVDs, Plus Five Free Bonus CDs.
Those two are both in New York City deals (again you do not have to live in New York to purchase them).
You can sign up for Groupon here. It's free to join.